It depends. Issa was not above using very basic words, for bodily functions particularly. Colin Stewart Jones frequently uses 'street language', Marlene Mountain has used the F word in a few that I have seen. If you were intending to use a word which is usually unacceptable for minors and polite poetry groups then it may limit possible posting, publishing and performance opportunities. However, there are some areas of western culture where it would be not only acceptable but commonplace to use the F word in particular and a whole raft of words that you won't hear at a Vicar's tea party but which are an acceptable part of youth culture language. Unless you were writing specifically for street-language culture then of course it will be shocking and offensive to some people. What do you expect? That's no reason not to use it though if you think it is a necessary part of your poem.
So are you going to show it to us?